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1

Drug-like Properties: Concepts, Structure Design and Methods || Barriers to Drug Exposure in Living Systems

Kerns, Edward H.

Year:

2008

Language:

english

File:

PDF, 1.08 MB

english, 2008

2

Drug-Like Property Concepts in Pharmaceutical Design

Di, Li, Kerns, Edward, Carter, Guy

Journal:

Current Pharmaceutical Design

Year:

2009

Language:

english

File:

PDF, 369 KB

english, 2009

3

Combined application of parallel artificial membrane permeability assay and Caco-2 permeability assays in drug discovery

Edward H. Kerns, Li Di, Susan Petusky, Michele Farris, Rob Ley, Phil Jupp

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

4

Direct aqueous injection gas chromatography for the analysis of trace organics in water

P.G. Simmonds, Edward Kerns

Journal:

Journal of Chromatography A

Year:

1979

Language:

english

File:

PDF, 732 KB

english, 1979

5

[Biotechnology: Pharmaceutical Aspects] Optimizing the “Drug-Like” Properties of Leads in Drug Discovery Volume IV || Solubility, Solubilization and Dissolution in Drug Delivery During Lead Optimization

Borchardt, Ronald T., Kerns, Edward H., Hageman, Michael J., Thakker, Dhiren R., Stevens, James L.

Year:

2006

Language:

english

File:

PDF, 1.27 MB

english, 2006

6

Experimental Determination of the Dynamics of a Mooring System

Kern Jr., Edward C., Milgram, Jerome H., Lincoln, Walter B.

Journal:

Journal of Hydronautics

Year:

1977

Language:

english

File:

PDF, 863 KB

english, 1977

7

De Veterum Macarismis; De coronarum apud antiquos vi atque usu; Intermediate Types among Primitive Folk; The House-Door on the Ancient Stage; Inscriptiones Graecae; De l'Aspect verbal en Latin ancien et particulierement dans Terence; De la Phrase a Verbe Etre dans l'Ionien d'Herodote; The Ottoman Empire, 1801-1913; Greek Philosophy. Part I. Thales to Plato;

S., J. L., Dirichlet, G. L., Kochling, J., Carpenter, Edward, Mooney, W. W., Kern, Otto, Barbelenet, D., Miller, William, Burnet, John

Journal:

The Journal of Hellenic Studies

Year:

1914

Language:

english

File:

PDF, 84 KB

english, 1914

8

Drug-like Properties: Concepts, Structure Design and Methods || Lead-like Compounds

Kerns, Edward H.

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

9

Automated deep learning design for medical image classification by health-care professionals with no coding experience: a feasibility study

Faes, Livia, Wagner, Siegfried K, Fu, Dun Jack, Liu, Xiaoxuan, Korot, Edward, Ledsam, Joseph R, Back, Trevor, Chopra, Reena, Pontikos, Nikolas, Kern, Christoph, Moraes, Gabriella, Schmid, Martin K, Si

Journal:

The Lancet Digital Health

Year:

2019

Language:

english

File:

PDF, 671 KB

english, 2019

10

LC/MS applications in drug development

Mike S. Lee, Edward H. Kerns

Journal:

Mass Spectrometry Reviews

Year:

1999

Language:

english

File:

PDF, 1.27 MB

english, 1999

11

ChemInform Abstract: Stability Challenges in Drug Discovery.

Li Di, Edward H. Kerns

Journal:

Year:

2010

File:

PDF, 15 KB

2010

12

High throughput physicochemical profiling for drug discovery

Edward H. Kerns

Journal:

Journal of Pharmaceutical Sciences

Year:

2001

Language:

english

File:

PDF, 440 KB

english, 2001

13

Monitoring and calibration system for neutrino flux measurement in a high energy dichromatic beam

R. Blair, B. Jin, D. Macfarlane, R.L. Messner, D.B. Novikoff, M.V. Purohit, P.S. Auchincloss, F. Sciulli, M.H. Shaevitz, D. Edwards, H. Edwards, H.E. Fisk, Y. Fukushima, Q.A. Kerns, T. Kondo, P.A. Rap

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

1984

Language:

english

File:

PDF, 1.34 MB

english, 1984

14

Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC–MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC–MS

Li Di, Edward H. Kerns, Susan Q. Li, Guy T. Carter

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 787 KB

english, 2007

15

Buspirone metabolite structure profile using a standard liquid chromatographic-mass spectrometric protocol

Edward H. Kerns, Robyn A. Rourick, Kevin J. Volk, Mike S. Lee

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 765 KB

english, 1997

16

Analysis of the clinical utility of a predictive chemosensitivity assay

Edward L. Korn, Vernon K. Sondak, Carl A. Bertelsen, David H. Kern

Journal:

Statistics in Medicine

Year:

1985

Language:

english

File:

PDF, 453 KB

english, 1985

17

Biological assay challenges from compound solubility: strategies for bioassay optimization

Li Di, Edward H. Kerns

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 167 KB

english, 2006

18

Rapid titration of carvedilol in patients with congestive heart failure: A randomized trial of automated telemedicine versus frequent outpatient clinic visits

Jeffrey Spaeder, Samer S. Najjar, Gary Gerstenblith, Gail Hefter, Linda Kern, James G. Palmer, Sheldon H. Gottlieb, Edward K. Kasper

Journal:

American Heart Journal

Year:

2006

Language:

english

File:

PDF, 241 KB

english, 2006

19

Factors affecting reoperations after anterior cervical discectomy and fusion within and outside of a Federal Drug Administration investigational device exemption cervical disc replacement trial

Kern Singh, Frank M. Phillips, Dan K. Park, Miguel A. Pelton, Howard S. An, Edward J. Goldberg

Journal:

The Spine Journal

Year:

2012

Language:

english

File:

PDF, 126 KB

english, 2012

20

Drug-like Properties: Concepts, Structure Design and Methods || Solubility

Kerns, Edward H.

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

21

Congenital lumbar spinal stenosis: a prospective, control-matched, cohort radiographic analysis

Kern Singh, Dino Samartzis, Alexander R. Vaccaro, Ahmad Nassr, Gunnar B. Andersson, S. Tim Yoon, Frank M. Phillips, Edward J. Goldberg, Howard S. An

Journal:

The Spine Journal

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

22

65. Factors Affecting Reoperations after ACDF Within and Outside of an FDA IDE Cervical TDR Trial

Kern Singh, Frank Phillips, Daniel Park, Howard An, Edward Goldberg

Journal:

The Spine Journal

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

23

Comparing outcomes of anterior cervical discectomy and fusion in workman's versus non–workman's compensation population

Edward J Goldberg, Kern Singh, U Van, Ralph Garretson, Howard S An

Journal:

The Spine Journal

Year:

2002

Language:

english

File:

PDF, 282 KB

english, 2002

24

Strategies to assess blood–brain barrier penetration

Di, Li, Kerns, Edward H, Carter, Guy T

Journal:

Expert Opinion on Drug Discovery

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

25

SPIE Proceedings [SPIE Symposium on Integrated Optoelectronics - San Jose, CA (Thursday 20 January 2000)] Light-Emitting Diodes: Research, Manufacturing, and Applications IV - High-brightness AlGaInN light-emitting diodes

Krames, Michael R., Christenson, G., Collins, Dave, Cook, Lou W., Craford, M. G., Edwards, A., Fletcher, Robert M., Gardner, Nathan F., Goetz, Werner K., Imler, William R., Johnson, Eric, Kern, R. Sco

Year:

2000

Language:

english

File:

PDF, 2.79 MB

english, 2000

26

Synthesis and Structure–Activity Relationship Studies of N -Benzyl-2-phenylpyrimidin-4-amine Derivatives as Potent USP1/UAF1 Deubiquitinase Inhibitors with Anticancer Activity against Nonsmall Cell Lung Cancer

Dexheimer, Thomas S., Rosenthal, Andrew S., Luci, Diane K., Liang, Qin, Villamil, Mark A., Chen, Junjun, Sun, Hongmao, Kerns, Edward H., Simeonov, Anton, Jadhav, Ajit, Zhuang, Zhihao, Maloney, David J

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.67 MB

english, 2014

27

Investigation of the mechanics of rail seat deterioration and methods to improve the abrasion resistance of concrete sleeper rail seats

Kernes, R. G., Shurpali, A. A., Edwards, J. R., Dersch, M. S., Lange, D. A., Barkan, C. P. L.

Journal:

Proceedings of the Institution of Mechanical Engineers Part F Journal of Rail and Rapid Transit

Year:

2014

Language:

english

File:

PDF, 682 KB

english, 2014

28

Efficient and Scalable Synthesis of 3,5,7-Trisubstituted 1 H -Indazoles as Potent IKK2 Inhibitors

Lin, Xichen, Busch-Petersen, Jakob, Deng, Jianghe, Edwards, Christine, Zhang, Zhaoguo, Kerns, Jeffrey

Journal:

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

29

A transseptal, transsphenoidal approach to the pituitary

Kern, Eugene B., Laws, Edward R., Randall, Raymond V., Westwood, William B.

Journal:

Postgraduate Medicine

Year:

1978

Language:

english

File:

PDF, 1.83 MB

english, 1978

30

The Patient-Centered Medical Home, Electronic Health Records, and Quality of Care

Kern, Lisa M., Edwards, Alison, Kaushal, Rainu

Journal:

Annals of Internal Medicine

Year:

2014

Language:

english

File:

PDF, 166 KB

english, 2014

31

The Critical Role of Passive Permeability in Designing Successful Drugs

Di, Li, Artursson, Per, Avdeef, Alex, Benet, Leslie, Houston, Brian, Kansy, Manfred, Kerns, Edward, LennernÃ¤s, Hans, Smith, Dennis, Sugano, Kiyohiko

Journal:

Year:

2020

File:

PDF, 1.27 MB

2020

32

The Coordinated Use of Tandem Mass Spectrometry and High Resolution Mass Spectrometry for the Structure Identification of the Kedarcidin Chromophore

Lee, Mike S., Klohr, Steven E., Kerns, Edward H., Volk, Kevin J., Leet, John E., Schroeder, Daniel R., Rosenberg, Ira E.

Journal:

Journal of Mass Spectrometry

Year:

1996

Language:

english

File:

PDF, 724 KB

english, 1996

33

Cellular uptake profile of paclitaxel using liquid chromatography tandem mass spectrometry

Edward H. Kerns, Susan E. Hill, David J. Detlefsen, Kevin J. Volk, Byron H. Long, Joan Carboni, Mike S. Lee

Journal:

Rapid Communications in Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 113 KB

english, 1998

34

Tandem mass spectrometry studies of green tea catechins. Identification of three minor components in the polyphenolic extract of green tea

Petra Miketova, Karl H. Schram, Jeff Whitney, Michael Li, Ron Huang, Edward Kerns, Susanne Valcic, Barbara N. Timmermann, Robyn Rourick, Steve Klohr

Journal:

Journal of Mass Spectrometry

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

35

Predictability of response to clinical thermochemotherapy by the clonogenic assay

Barry D. Mann, F. Kristian Storm, Donald L. Morton, Carl A. Bertelsen, Edward L. Korn, Larry R. Kaiser, David H. Kern

Journal:

Year:

1983

Language:

english

File:

PDF, 573 KB

english, 1983

36

Chemosensitivity testing of human solid tumors. A review of 1582 assays with 258 clinical correlations

Carl A. Bertelsen, Vernon K. Sondak, Barry D. Mann, Edward L. Korn, David H. Kern

Journal:

Year:

1984

Language:

english

File:

PDF, 593 KB

english, 1984

37

Psychiatric disorders among obese binge eaters

Marsha D. Marcus, Rena R. Wing, Linda Ewing, Edward Kern, William Gooding, Michael McDermott

Journal:

Journal of Eating Disorders

Year:

1990

Language:

english

File:

PDF, 621 KB

english, 1990

38

Migration of copper through high purity poly(methyl methacrylate)

Edward L. Kern, George Eierman, Edward G. Bobalek, Selby M. Skinner

Journal:

Journal of Applied Polymer Science

Year:

1959

Language:

english

File:

PDF, 167 KB

english, 1959

39

Electromechanical hysteresis measurements: A new tool for investigation of the properties of plastics

Edward L. Kern, Selby M. Skinner

Journal:

Journal of Applied Polymer Science

Year:

1962

Language:

english

File:

PDF, 1.21 MB

english, 1962

40

Immunolocalization of chick periostin protein in the developing heart

Christine B. Kern, Stanley Hoffman, Ricardo Moreno, Brook J. Damon, Russell A. Norris, Edward L. Krug, Roger R. Markwald, Corey H. Mjaatvedt

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

2005

Language:

english

File:

PDF, 586 KB

english, 2005

41

Rapid screening of fermentation broths for flavones using tandem mass spectrometry

Mike S. Lee, Derek J. Hook, Edward H. Kerns, Kevin J. Volk, Ira E. Rosenberg

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1993

Language:

english

File:

PDF, 310 KB

english, 1993

42

Stability Challenges in Drug Discovery

Li Di, Edward H. Kerns

Journal:

Chemistry & Biodiversity

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

43

Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery—Building chiral technology toolboxes

Oliver McConnell, Alvin Bach II, Carl Balibar, Neal Byrne, Yanxuan Cai, Guy Carter, Michael Chlenov, Li Di, Kristi Fan, Igor Goljer, Yanan He, Don Herold, Michael Kagan, Edward Kerns, Frank Koehn, Chr

Journal:

Year:

2007

Language:

english

File:

PDF, 676 KB

english, 2007

44

Neuroglial response to sciatic neurectomy. I. Light microscopy and autoradiography,

James M. Kerns, Edward J. Hinsman

Journal:

The Journal of Comparative Neurology

Year:

1973

Language:

english

File:

PDF, 1.18 MB

english, 1973

45

Neuroglial response to sciatic neurectomy. II. Electron microscopy,

James M. Kerns, Edward J. Hinsman

Journal:

The Journal of Comparative Neurology

Year:

1973

Language:

english

File:

PDF, 2.13 MB

english, 1973

46

Surgical approaches to the pituitary gland, with emphasis on the transseptal route

Dr. Thomas J. McDonald, Dr. Eugene B. Kern, Dr. Edward R. Laws, Dr. Bruce W. Pearson

Journal:

Year:

1979

Language:

english

File:

PDF, 665 KB

english, 1979

47

National Institutes of Health consensus development conference statement: Management of hepatitis B

Michael F. Sorrell, Edward A. Belongia, Jose Costa, Ilana F. Gareen, Jean L. Grem, John M. Inadomi, Earl R. Kern, James A. McHugh, Gloria M. Petersen, Michael F. Rein, Doris B. Strader, Hartwell T. Tr

Journal:

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

48

Simultaneous determination of 2-arachidonoylglycerol, 1-arachidonoylglycerol and arachidonic acid in mouse brain tissue using liquid chromatography/tandem mass spectrometry

Mei-Yi Zhang, Ying Gao, Joan Btesh, Natasha Kagan, Edward Kerns, Tarek A. Samad, Pranab K. Chanda

Journal:

Journal of Mass Spectrometry

Year:

2010

Language:

english

File:

PDF, 265 KB

english, 2010

49

Hybrid triple quadrupole-linear ion trap mass spectrometry in fragmentation mechanism studies: application to structure elucidation of buspirone and one of its metabolites

Mei-Yi Zhang, Nadia Pace, Edward H. Kerns, Teresa Kleintop, Natasha Kagan, Takeo Sakuma

Journal:

Journal of Mass Spectrometry

Year:

2005

Language:

english

File:

PDF, 227 KB

english, 2005

50

Experimental design on single-time-point high-throughput microsomal stability assay

Li Di, Edward H. Kerns, Ning Gao, Susan Q. Li, Youping Huang, Jim L. Bourassa, Donna M. Huryn

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004